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> home > Products > Primary Antibodies > Signal Transduction > Anti-TFAP2A / AP-2 Antibody (clone 2G5)
Anti-TFAP2A / AP-2 Antibody (clone 2G5)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P05549 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1,k |
| Clone Names | 2G5 |
| Calculated MW | 48062 Da |
| Dilution | ELISA, IHC-P (5 µg/ml), WB (1:500 - 1:1000) |
| Gene ID | 7020 |
|---|---|
| Alias Symbol | TFAP2A |
| Other Names | TFAP2A, Activator protein 2, AP-2, AP-2a, AP2TF, AP-2alpha, BOFS, TFAP2, Transcription factor AP-2, AP-2 transcription factor, AP2-alpha |
| Target/Specificity | Human TFAP2A |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-TFAP2A / AP-2 Antibody (clone 2G5) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TFAP2A |
|---|---|
| Synonyms | AP2TF, TFAP2 |
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. |
| Cellular Location | Nucleus. |
Research Areas
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Application Protocols
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$ 533.50
Cat# ALS17688
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