|Application ||WB, IHC-P, IF, E|
|Calculated MW||72890 Da|
|Dilution||ELISA, IF (10 µg/ml), IHC-P (1.2 - 5 µg/ml), WB (1:500 - 1:1000)|
|Other Names||MED17, CRSP77, CRSP complex subunit 6, CRSP6, DRIP77, Mediator complex subunit 17, TRAP80, ARC77, DRIP80|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-MED17 / TRAP80 Antibody (clone 4D4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ARC77, CRSP6, DRIP77, DRIP80, TRAP80|
|Function||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|
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