|Application ||WB, IHC-P, E|
|Calculated MW||55756 Da|
|Dilution||ELISA, IHC-P (3 - 5 µg/ml), WB|
|Other Names||SEPT8, KIAA0202, SEP2, Septin-8, Septin 8|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-SEPT8 / Septin 8 Antibody (clone 1G3-7D1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.|
|Tissue Location||Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary|
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