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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-FOLH1 / PSMA Antibody (aa44-750, clone GCP-04)   

Anti-FOLH1 / PSMA Antibody (aa44-750, clone GCP-04)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q04609
Predicted Human, Rat, Pig
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names GCP-04
Calculated MW 84331 Da
Dilution IHC-P (10 µg/ml), WB
Additional Information
Gene ID 2346
Alias Symbol FOLH1
Other Names FOLH1, Folate hydrolase 1, GCPII, Glutamate carboxypeptidase II, Folate hydrolase, GCP2, NAALAD1, NAALAdase, NAALADase I, PSM, FGCP, FOLH, Glutamate carboxylase II, Glutamate carboxypeptidase 2, MGCP, PSMA
Target/Specificity Recognizes Prostate Specific Membrane Antigen. Species cross-reactivity: Human, rat and porcine.
Reconstitution & Storage Protein A purified
PrecautionsAnti-FOLH1 / PSMA Antibody (aa44-750, clone GCP-04) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOLH1
Function Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem Also expressed in fetal liver and kidney. Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-2 is also found in normal prostate as well as in brain and liver. Isoform PSMA-9 is specifically expressed in prostate cancer
Research Areas
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$ 395.00
Cat# ALS17759
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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