Anti-TNNT2 / CTNT Antibody (clone 13-11)
Mouse Anti Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IF |
---|---|
Primary Accession | P45379 |
Predicted | Human, Mouse, Rat, Rabbit, Monkey, Chicken, Sheep, Bovine, Horse, Dog |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 13-11 |
Calculated MW | 35924 Da |
Dilution | IF, IHC-P (10 µg/ml) |
Gene ID | 7139 |
---|---|
Alias Symbol | TNNT2 |
Other Names | TNNT2, Cardiomyopathy, hypertrophic 2, CMPD2, CMD1D, CMH2, Cardiac muscle troponin T, Cardiac Troponin T, LVNC6, TnTC, Troponin T type 2 (cardiac), Troponin T, cardiac muscle, Troponin T2, cardiac, CTnT, RCM3 |
Target/Specificity | FMPNLVPPKI (5 region of the cardiac gene exon 10) |
Reconstitution & Storage | Protein G purified |
Precautions | Anti-TNNT2 / CTNT Antibody (clone 13-11) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TNNT2 |
---|---|
Function | Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
Tissue Location | Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart |
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