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Anti-SHANK2 / SHANK Antibody (aa331-380)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UPX8
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 158822 Da
Dilution ELISA, IHC-P (1:50), WB
Additional Information
Gene ID 22941
Alias Symbol SHANK2
Other Names SHANK2, AUTS17, Cortactin binding protein 1, CTTNBP1, CORTBP1, SPANK-3, SHANK, Cortactin-binding protein 1, GKAP/SAPAP interacting protein, KIAA1022, ProSAP1
Target/Specificity SHANK2 Antibody detects endogenous levels of total SHANK2 protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-SHANK2 / SHANK Antibody (aa331-380) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CORTBP1, KIAA1022, PROSAP1
Function Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Cellular Location Apical cell membrane. Cytoplasm. Cell junction, synapse Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, growth cone Cell projection, dendritic spine. Note=Colocalizes with cortactin in growth cones in differentiating hippocampal neurons. Colocalized with PDE4D to the apical membrane of colonic crypt cells (By similarity).
Tissue Location Isoform 3 is present in epithelial colonic cells (at protein level).
Research Areas
Citations (0)

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$ 395.00
Cat# ALS17818
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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