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Anti-MAP3K11 / MLK3 Antibody (clone 3D11)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-F, E
Primary Accession Q16584
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 3D11
Calculated MW 92688 Da
Dilution ELISA, IHC-Fr (1:50), WB
Additional Information
Gene ID 4296
Alias Symbol MAP3K11
Other Names MAP3K11, Mixed lineage kinase 3, MLK3, Protein-tyrosine kinase PTK1, PTK1, SPRK, MLK-3, MEKK11
Target/Specificity Human MAP3K11
Reconstitution & Storage Protein A purified
PrecautionsAnti-MAP3K11 / MLK3 Antibody (clone 3D11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP3K11 (HGNC:6850)
Function Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Location is cell cycle dependent
Tissue Location Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain.
Research Areas
Citations (0)

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$ 450.00
Cat# ALS17851
Size:
Quantity:
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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