|Application ||WB, IHC-P, E|
|Calculated MW||45349 Da|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (0.1 - 0.3 µg/ml)|
|Other Names||TFB2M, H-mtTFB, H-mtTFB2, HTFB2M, MtTFB2, Hkp1, NS5ATP5|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-TFB2M Antibody (aa325-338) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.|
|Tissue Location||Ubiquitously expressed.|
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