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Anti-E4F1 / E4F Antibody (clone 4B10)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q66K89
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 4B10
Calculated MW 83496 Da
Dilution ELISA, IF (10 µg/ml), IHC-P (5 µg/ml), WB
Additional Information
Gene ID 1877
Alias Symbol E4F1
Other Names E4F1, E4F, E4F transcription factor 1, p50E4F, Transcription factor E4F1, Transcription factor E4F, p120E4F, p120e4f transcription factor
Target/Specificity Human E4F1 / E4F
Reconstitution & Storage Protein A purified
PrecautionsAnti-E4F1 / E4F Antibody (clone 4B10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name E4F1
Synonyms E4F
Function May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.
Cellular Location Nucleus, nucleoplasm. Cytoplasm. Note=A small fraction is detected in the cytoplasm. Excluded from the nucleolus where it is targeted upon CDKN2A overexpression Localizes to the mitotic spindle during embryogenesis (By similarity).
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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$ 450.00
Cat# ALS17906
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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