|Application ||IHC-P, E|
|Calculated MW||38457 Da|
|Dilution||ELISA (1:32000), IHC-P (5 µg/ml)|
|Other Names||RAD51AP1, PIR51, RAD51-associated protein 1, RAD51 associated protein 1, RAD51-interacting protein|
|Target/Specificity||Human RAD51AP1. This antibody is expected to recognise both reported isoforms.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-RAD51AP1 Antibody (aa340-352) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.|
|Cellular Location||Nucleus. Note=Colocalizes with RAD51 to multiple nuclear foci.|
|Tissue Location||Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes|
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