|Application ||WB, IHC-P, E|
|Calculated MW||79435 Da|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (0.3 - 1 µg/ml)|
|Other Names||TSPYL2, CDA1, CINAP, DENTT, CTCL, CTCL-associated antigen se20-4, Cell division autoantigen 1, HRIHFB2216, Nuclear protein of 79 kDa, NP79, TSPY-like protein 2, SE20-4, SE204, TSPY-like 2, CTCL tumor antigen se20-4, TSPX|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-TSPYL2 / DENTT Antibody (aa441-454) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CDA1, DENTT, TSPX|
|Function||Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.|
|Cellular Location||Nucleus. Cytoplasm Note=Enriched in transcriptionally active regions of chromatin in neurons.|
|Tissue Location||Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas|
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