|Application ||IHC-P, E, Func, Flo|
|Calculated MW||30619 Da|
|Dilution||ELISA, Flo, Func, IHC-P (10 µg/ml)|
|Other Names||CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5|
|Target/Specificity||CD40 molecule of about 44 kd.|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-CD40 Antibody (clone EA-5, Azide-free) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.|
|Cellular Location||Isoform I: Cell membrane; Single-pass type I membrane protein|
|Tissue Location||B-cells and in primary carcinomas.|
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