Anti-CD40 Antibody (clone EA-5, Azide-free)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E, Func, FC |
---|---|
Primary Accession | P25942 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | EA-5 |
Calculated MW | 30619 Da |
Dilution | ELISA, Flo, Func, IHC-P (10 µg/ml) |
Gene ID | 958 |
---|---|
Alias Symbol | CD40 |
Other Names | CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5 |
Target/Specificity | CD40 molecule of about 44 kd. |
Reconstitution & Storage | Protein A purified |
Precautions | Anti-CD40 Antibody (clone EA-5, Azide-free) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD40 |
---|---|
Synonyms | TNFRSF5 |
Function | Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). |
Cellular Location | [Isoform I]: Cell membrane; Single-pass type I membrane protein |
Tissue Location | B-cells and in primary carcinomas. |
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