Anti-ZHX2 / RAF Antibody (aa751-800)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | Q9Y6X8 |
Predicted | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 92307 Da |
Dilution | ELISA, IHC-P (1:50) |
Gene ID | 22882 |
---|---|
Alias Symbol | ZHX2 |
Other Names | ZHX2, AFR1, Alpha-fetoprotein regulator 1, AFP regulator 1, KIAA0854, Regulator of AFP, Transcription factor ZHX2, Zinc fingers and homeoboxes 2, Zinc-fingers and homeoboxes 2, RAF |
Target/Specificity | ZHX2 Antibody detects endogenous levels of total ZHX2 protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-ZHX2 / RAF Antibody (aa751-800) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZHX2 |
---|---|
Synonyms | AFR1, KIAA0854, RAF |
Function | Acts as a transcriptional repressor (PubMed:12741956). Represses the promoter activity of the CDC25C gene stimulated by NFYA (PubMed:12741956). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598} Note=Colocalizes with EFNB1 intracellular domain in the nucleus {ECO:0000250|UniProtKB:Q8C0C0} |
Tissue Location | Ubiquitously expressed. Expressed in podocytes. |
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