|Application ||WB, IHC-P, E|
|Calculated MW||47464 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||PSMD11, 26s proteasome subunit 9, S9, Rpn6, p44.5|
|Target/Specificity||PSMD11 Antibody detects endogenous levels of total PSMD11 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-PSMD11 Antibody (aa271-320) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.|
|Cellular Location||Nucleus. Cytoplasm, cytosol|
|Tissue Location||Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate|
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