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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-PSMD11 Antibody (aa271-320)
Anti-PSMD11 Antibody (aa271-320)
Rabbit Anti Human Polyclonal Antibody
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Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O00231 |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 47464 Da |
| Dilution | ELISA, IHC-P (1:50), WB |
| Gene ID | 5717 |
|---|---|
| Alias Symbol | PSMD11 |
| Other Names | PSMD11, 26s proteasome subunit 9, S9, Rpn6, p44.5 |
| Target/Specificity | PSMD11 Antibody detects endogenous levels of total PSMD11 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-PSMD11 Antibody (aa271-320) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PSMD11 |
|---|---|
| Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity. |
| Cellular Location | Nucleus. Cytoplasm, cytosol |
| Tissue Location | Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate |
Research Areas
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