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Anti-POSTN / Periostin Antibody (clone Stiny-1, Biotin)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IHC-F, E
Primary Accession Q15063
Predicted Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names Stiny-1
Calculated MW 93314 Da
Dilution ELISA, IHC-Fr (1:200 - 1:500), IHC-P (15 µg/ml), WB (1:1000)
Additional Information
Gene ID 10631
Alias Symbol POSTN
Other Names POSTN, OSF2, PDLPOSTN, Periostin isoform thy6, Periostin isoform thy8, RP11-412K4.1, OSF-2, Osteoblast-specific factor 2, Periostin, Periostin isoform thy2, Periostin isoform thy4, PN
Target/Specificity Recognizes human and mouse periostin
PrecautionsAnti-POSTN / Periostin Antibody (clone Stiny-1, Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POSTN
Synonyms OSF2
Function Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).
Cellular Location Golgi apparatus {ECO:0000250|UniProtKB:Q62009}. Secreted Secreted, extracellular space, extracellular matrix Note=Colocalizes with BMP1 in the Golgi {ECO:0000250|UniProtKB:Q62009}
Tissue Location Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor Overexpressed in breast cancers.
Research Areas
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$ 450.00
Cat# ALS18157
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