|Application ||WB, IHC-P|
|Calculated MW||36154 Da|
|Dilution||IHC-P (1:100), WB (1:1000)|
|Other Names||APOE, AD2, Apo-E, Apolipoprotein E3, Apolipoprotein E, LDLCQ5, LPG|
|Target/Specificity||Human APOE / Apolipoprotein E|
|Reconstitution & Storage||Ammonium sulfate precipitation|
|Precautions||Anti-APOE / Apolipoprotein E Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.|
|Tissue Location||Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle|
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