Anti-PON1 / ESA Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P27169 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 39731 Da |
Dilution | ELISA, IHC-P (10 µg/ml), WB |
Gene ID | 5444 |
---|---|
Alias Symbol | PON1 |
Other Names | PON1, A-esterase 1, Aromatic esterase 1, Esterase A, ESA, K-45, MVCD5, Paraoxonase 1, PON 1, Serum aryldialkylphosphatase 1, Arylesterase B-type, Paraoxonase B-type, PON, Serum aryldiakylphosphatase |
Target/Specificity | Human PON1 / ESA |
Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
Precautions | Anti-PON1 / ESA Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PON1 |
---|---|
Synonyms | PON |
Function | Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. |
Cellular Location | Secreted, extracellular space. |
Tissue Location | Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. |
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