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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1)
Anti-Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IP, FC |
|---|---|
| Primary Accession | P35613 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | MEM-M6/1 |
| Calculated MW | 42200 Da |
| Dilution | Flo, IHC-P (10 µg/ml), IP, WB |
| Gene ID | 682 |
|---|---|
| Alias Symbol | BSG |
| Other Names | BSG, 5F7, Basigin, Basigin (Ok blood group), CD147 antigen, Collagenase stimulatory factor, EMMPRIN, OK, OK blood group antigen, TCSF, CD147, M6 |
| Reconstitution & Storage | Purified |
| Precautions | Anti-Basigin / Emmprin / CD147 Antibody (clone MEM-M6/1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BSG (HGNC:1116) |
|---|---|
| Function | [Isoform 1]: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857). |
| Cellular Location | Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. [Isoform 2]: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453}. Endosome Endoplasmic reticulum membrane; Single- pass type I membrane protein {ECO:0000250|UniProtKB:P26453} Basolateral cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453} [Isoform 4]: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P26453} |
| Tissue Location | [Isoform 1]: Retina-specific (PubMed:25957687). Expressed in retinal cone photoreceptors (at protein level) (PubMed:25957687). [Isoform 3]: Highly expressed in the bone marrow, fetal liver, lung, testis and thymus. |
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