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Anti-SYNE3 / C14orf49 Antibody (Internal)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6ZMZ3
Predicted Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 112216 Da
Dilution ICC (1:100 - 1:500), IF, IHC-P (1:100), WB (1:500 - 1:1000)
Additional Information
Gene ID 161176
Alias Symbol SYNE3
Other Names SYNE3, C14orf49, Nesp3, NET53, Nesprin-3
Target/Specificity Recognizes endogenous levels of SYNE3 protein.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-SYNE3 / C14orf49 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYNE3
Synonyms C14orf49
Function Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow- induced centrosome polarization and directional migration in aortic endothelial cells.
Cellular Location Nucleus outer membrane; Single-pass type IV membrane protein. Nucleus envelope. Rough endoplasmic reticulum
Tissue Location Expressed in aortic endothelial cells (at protein level).
Research Areas
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$ 395.00
Cat# ALS18230
(40 western blots)
Availability: 5 days
Bulk Size
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