|Application ||WB, IHC-P, E|
|Calculated MW||45251 Da|
|Dilution||ELISA, IHC-P (5 µg/ml), WB|
|Other Names||IHH, Indian hedgehog, Indian hedgehog homolog, Indian hedgehog protein, HHG2, BDA1, HHG-2|
|Reconstitution & Storage||Caprylic acid and ammonium sulfate precipitation|
|Precautions||Anti-IHH Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).|
|Cellular Location||Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface. Cell membrane.|
|Tissue Location||Expressed in embryonic lung, and in adult kidney and liver|
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