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Anti-DKK3 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBP4
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 38390 Da
Dilution IHC-P (1:100), WB (1:500 - 1:2000)
Additional Information
Gene ID 27122
Alias Symbol DKK3
Other Names DKK3, Dickkopf-3, Dkk-3, Dickkopf homolog 3, Dickkopf-related protein 3, HDkk-3, Regulated in glioma, RIG-like 7-1, REIC, RIG-like 5-6
Target/Specificity Human DKK3
Reconstitution & Storage Affinity purified
PrecautionsAnti-DKK3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DKK3
Synonyms REIC
Function Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Cellular Location Secreted.
Tissue Location Highest expression in heart, brain, and spinal cord. {ECO:0000269|PubMed:10570958, ECO:0000269|Ref.4}
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18333
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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