Anti-Complement C9 Antibody (aa181-230)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P02748 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 63173 Da |
Dilution | ELISA, IHC-P (1:50), WB |
Gene ID | 735 |
---|---|
Alias Symbol | C9 |
Other Names | C9, Complement C9, Complement component 9, Complement component C9 |
Target/Specificity | C9 Antibody detects endogenous levels of total C9 protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-Complement C9 Antibody (aa181-230) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | C9 |
---|---|
Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (PubMed:9634479, PubMed:9212048, PubMed:26841934). C9 is the pore-forming subunit of the MAC (PubMed:4055801, PubMed:26841934, PubMed:30111885). |
Cellular Location | Secreted. Target cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore |
Tissue Location | Plasma (at protein level). |
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