|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Rabbit, Bovine|
|Calculated MW||57942 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||KCNC1, KShIIIB, KV3.1, Raw2, Shaw22, KV4, NGK2|
|Target/Specificity||Recognizes endogenous levels of Kv3.1 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-KCNC1 / Kv3.1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
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