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Anti-ADCK3 / CABC1 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
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Application 
| WB, IHC-P, IF, ICC |
|---|---|
| Primary Accession | Q8NI60 |
| Predicted | Human, Mouse, Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 71950 Da |
| Dilution | ICC (1:100 - 1:500), IF (1:100 - 1:500), IHC-P (1:100), WB (1:500 - 1:1000) |
| Gene ID | 56997 |
|---|---|
| Alias Symbol | ADCK3 |
| Other Names | ADCK3, Chaperone-ABC1-like, SCAR9, ARCA2, CABC1, Coenzyme Q8 homolog, COQ10D4, COQ8 |
| Target/Specificity | Recognizes endogenous levels of CABC1 protein. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-ADCK3 / CABC1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | COQ8A {ECO:0000303|PubMed:27499294, ECO:0000312|HGNC:HGNC:16812} |
|---|---|
| Function | Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144, PubMed:21296186, PubMed:25540914, PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:25498144, PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (PubMed:25498144, PubMed:27499294). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144). |
| Cellular Location | Mitochondrion. Membrane; Single-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:25216398} |
| Tissue Location | Widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle. |
Research Areas
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$ 395.00
Cat# ALS18439
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