|Application ||IHC, IHC-P, E|
|Calculated MW||21841 Da|
|Dilution||ELISA (0.05 - 0.2 µg/ml), IHC (1 - 10 µg/ml), IHC-P (15 µg/ml)|
|Other Names||IGF1, IGF-IA, IGF-IB, IGFI, IBP1, IGF-I, Insulin-like growth factor 1, Insulin-like growth factor I, Insulin-like growth factor IA, Insulin-like growth factor IB, Mechano growth factor, Somatomedin-C, IGF1A, MGF|
|Target/Specificity||No cross reactivity with IGF-II or IGF-BP4.|
|Reconstitution & Storage||Protein A purified|
|Precautions||Anti-IGF1 Antibody (clone 1E11A3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.|
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