|Application ||WB, IHC-P, IF|
|Predicted||Human, Mouse, Rat|
|Calculated MW||21646 Da|
|Dilution||IF (1:50 - 1:200), IHC-P (1:100), WB (1:500 - 1:2000)|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-MGMT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|
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