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Anti-NOTCH3 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UM47
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 243631 Da
Dilution IF, IHC-P (1:100), WB
Additional Information
Gene ID 4854
Alias Symbol NOTCH3
Other Names NOTCH3, CASIL, CADASIL, Notch 3, Notch (Drosophila) homolog 3, Notch homolog 3, Notch homolog 3 (Drosophila)
Target/Specificity Human NOTCH3
Reconstitution & Storage Affinity purified
PrecautionsAnti-NOTCH3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Ubiquitously expressed in fetal and adult tissues
Research Areas
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$ 395.00
Cat# ALS18598
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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