|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||26144 Da|
|Dilution||IHC-P (1:100), WB|
|Other Names||MBL2, Mannan-binding lectin, Mannan-binding protein, MBL2D, MBPD, MBL, Mannose-binding lectin, MBP-C, MBP1, COLEC1, Collectin-1, HSMBPC, Mannose-binding protein C|
|Target/Specificity||Human MBL2 / Mannose Binding Protein|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-MBL2 / Mannose Binding Protein Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.|
|Tissue Location||Plasma protein produced mainly in the liver.|
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