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Anti-MORF4L1 / MRG15 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBU8
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 41474 Da
Dilution IF, IHC-P (1:100), WB
Additional Information
Gene ID 10933
Alias Symbol MORF4L1
Other Names MORF4L1, Eaf3, Mortality factor 4 like 1, HsT17725, Protein MSL3-1, MEAF3, MORFRG15, MRG15, FWP006, MORF-related gene 15 protein, S863-6
Target/Specificity Human MORF4L1 / MRG15
Reconstitution & Storage Affinity purified
PrecautionsAnti-MORF4L1 / MRG15 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MORF4L1
Synonyms MRG15
Function Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.
Cellular Location Nucleus.
Research Areas
Citations (0)

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$ 395.00
Cat# ALS18623
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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