|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||43573 Da|
|Dilution||IHC-P (1:100), WB|
|Other Names||SIRT3, HSIRT3, Sir2-like 3, SIR2-like protein 3, SIR2L3, Sirtuin 3, Sirtuin type 3|
|Target/Specificity||Human SIRT3 / Sirtuin 3|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-SIRT3 / Sirtuin 3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.|
|Cellular Location||Mitochondrion matrix|
|Tissue Location||Widely expressed.|
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