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H1L Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P20495 |
| Reactivity | Vaccinia Virus |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone/Animal Names | 20CT26.44.10.3 / 20CT26.44.10.14 |
| Calculated MW | 19672 Da |
| Other Names | Dual specificity protein phosphatase H1, 313-, Late protein H1, H1L |
|---|---|
| Target/Specificity | Purified recombinant H1L fusion protein was used to produced this monoclonal antibody. |
| Dilution | WB~~1:500~1000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | H1L Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OPG106 |
|---|---|
| Function | Serine/tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated host STAT1 and blocking interferon (IFN)-stimulated innate immune responses. Dephosphorylates the OPG144 protein. |
| Cellular Location | Virion {ECO:0000250|UniProtKB:P07239}. Host cytoplasm {ECO:0000250|UniProtKB:P07239}. Note=Approximately 200 molecules of OPG106 are packaged within the virion and are essential for the viability of the virus. {ECO:0000250|UniProtKB:P07239} |
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Provided below are standard protocols that you may find useful for product applications.
Background
This Protein shows activity toward tyrosine-protein phosphate as well as with serine-protein phosphate.
References
Goebel S.J., Virology 179:247-266(1990). Goebel S.J., Virology 179:517-563(1990).
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