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ALDH6A1 AntibodyPurified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AM1838b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AM1838b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
ALDH6A1 Antibody - Product info | |
| Application | WB
|
| Primary Accession | Q02252 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | IgG1,IgK |
| Clone Names | 147CT8.3.4 |
| Calculated MW | 57840 Da |
ALDH6A1 Antibody - Additional info | |
| Gene ID 4329 | |
| Other Names ALDH6A1; MMSDH; Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Aldehyde dehydrogenase family 6 member A1 | |
| Target/Specificity This ALDH6A1 antibody is generated from mouse immunized with ALDH6A1 recombinant protein. | |
| Dilution WB~~1:1000 | |
| Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ALDH6A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
ALDH6A1 Antibody - Protein Information | |
| Name ALDH6A1 | |
| Synonyms MMSDH | |
| Function Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | |
| Cellular Location Mitochondrion. | |
ALDH6A1 Antibody - Related products
AM1838a: ALDH6A1 Antibody (Ascites)
AP1469a: ALDH6A1 Antibody (N-term)
AP1469b: ALDH6A1 Antibody (C-term)
RI10237: ALDH6A1 predesign siRNA
DC01554: Human ALDH6A1 cDNA Clone
LY11652a: ALDH6A1 Over-expression Lysate
ALDH6A1 Antibody - Application data
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ALDH6A1 Antibody (Cat. #AM1838b) western blot analysis in HepG2, MCF-7,T47D cell line lysates (35ug/lane).This demonstrates the ALDH6A1 antibody detected the ALDH6A1 protein (arrow).
ALDH6A1 Antibody - Research Areas
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BACKGROUND
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, et al. J Hum Genet, 2009 Jun. PMID 19343046. Physical mapping of CHX10, ALDH6A1, and ABCD4 on bovine chromosome 10q34. Kuiper H, et al. Cytogenet Genome Res, 2005. PMID 15909363. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334. The human plasma proteome: a nonredundant list developed by combination of four separate sources. Anderson NL, et al. Mol Cell Proteomics, 2004 Apr. PMID 14718574.
