|Application ||WB, E|
|Calculated MW||33784 Da|
|Other Names||Developmental pluripotency-associated protein 2, Pluripotent embryonic stem cell-related gene 1 protein, DPPA2, PESCRG1|
|Target/Specificity||This DPPA2 monoclonal antibody is generated from mouse immunized with DPPA2 recombinant protein.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DPPA2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes.|
|Tissue Location||Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
DPPA2 may play a role in maintaining cell pluripotentiality.
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Tchabo, N.E., et al. Cancer Immun. 9, 6 (2009) :
John, T., et al. Clin. Cancer Res. 14(11):3291-3298(2008)
Monk, M., et al. Mol. Hum. Reprod. 14(6):347-355(2008)
Du, J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21(6):542-547(2004)
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