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ITGAX/CD11c Antibody (N-term)

Mouse Monoclonal Antibody (Mab)

  • WB - ITGAX/CD11c Antibody (N-term) AM2013b
    ITGAX/CD11c Antibody (N-term) (Cat. #AM2013b) western blot analysis in ZR-75-1 cell line lysates (35μg/lane).This demonstrates the ITGAX/CD11c antibody detected the ITGAX/CD11c protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20702
Other Accession NP_000878.2
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 428CT12.2.6.4
Calculated MW 127829 Da
Antigen Region 246-274 aa
Additional Information
Gene ID 3687
Other Names Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C
Target/Specificity This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c.
Dilution WB~~1:100~500
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsITGAX/CD11c Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD11C
Function Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Predominantly expressed in monocytes and granulocytes
Research Areas
Citations (0)

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This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.


Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) :
Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(33):14727-14732(2010)
Lindsay, R.W., et al. J. Immunol. 185(3):1513-1521(2010)
Kraus, T.S., et al. Am. J. Clin. Pathol. 134(2):271-277(2010)
Quist, S.R., et al. Acta Derm. Venereol. 90(4):429-430(2010)

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$ 295.00
$ 99.00
Cat# AM2013b
(40 western blots)
Availability: In Stock
Bulk Size
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