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IGHG1 Antibody (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • WB - IGHG1 Antibody (Ascites) AM2055a
    IGHG1 Antibody (Cat. #AM2055a) western blot analysis in HepG2 cell line lysates (35μg/lane).This demonstrates the IGHG1 antibody detected the IGHG1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P01857
Other Accession P01860
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 452CT2.3.2
Calculated MW 36106 Da
Antigen Region 154-180 aa
Additional Information
Other Names Ig gamma-1 chain C region, IGHG1
Target/Specificity This IGHG1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 154-180 amino acids from human IGHG1.
Dilution WB~~1:100~1600
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIGHG1 Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGHG1 {ECO:0000303|PubMed:11340299, ECO:0000303|Ref.11}
Function Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location Secreted. Cell membrane
Research Areas
Citations (0)

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Background

The function of this protein remains unknown.

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$ 295.00
Cat# AM2055a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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