|Application ||WB, E|
|Other Accession||A2V9Z4, NP_000468.1, P35747|
|Calculated MW||69367 Da|
|Antigen Region||540-569 aa|
|Other Names||Serum albumin, ALB|
|Target/Specificity||This ALB antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 540-569 amino acids from human ALB.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ALB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.|
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Provided below are standard protocols that you may find useful for product applications.
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.
Schelleman, H., et al. Br J Clin Pharmacol 70(3):393-399(2010)
Minchiotti, L., et al. Hum. Mutat. 29(8):1007-1016(2008)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Sugio, S., et al. Protein Eng. 12(6):439-446(1999)
Sakamoto, Y., et al. Biochim. Biophys. Acta 1252(2):209-216(1995)
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