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CTGF Antibody

Mouse Monoclonal Antibody (Mab)

  • WB - CTGF Antibody AM2095b
    CTGF Antibody(Cat. #AM2095b) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the CTGF antibody detected the CTGF protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29279
Other Accession Q9R1E9, O19113, P29268, NP_001892.1
Reactivity Human
Predicted Mouse, Pig, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names 558CT34.4.4
Calculated MW 38091 Da
Antigen Region 166-193 aa
Additional Information
Gene ID 1490
Other Names Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8, CTGF, CCN2, HCS24, IGFBP8
Target/Specificity This CTGF antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from human CTGF.
Dilution WB~~1:100
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTGF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CCN2, HCS24, IGFBP8
Function Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Cellular Location Secreted, extracellular space, extracellular matrix. Secreted
Tissue Location Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested
Research Areas
Citations (0)

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The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq].


Behrens, M.E., et al. Oncogene 29(42):5667-5677(2010)
Cunningham, J.L., et al. Eur. J. Endocrinol. 163(4):691-697(2010)
Ito, Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F545-F558 (2010) :
Adler, S.G., et al. Clin J Am Soc Nephrol 5(8):1420-1428(2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :

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Cat# AM2095b
(40 western blots)
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