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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AGT Antibody (N-term)   

AGT Antibody (N-term)

Mouse Monoclonal Antibody (Mab)

  • WB - AGT Antibody (N-term) AM2173b
    AGT Antibody (N-term) (Cat. #AM2173b) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the AGT antibody detected the AGT protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01019
Other Accession NP_000020
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 656CT5.8.4
Calculated MW 53154 Da
Antigen Region 37-65 aa
Additional Information
Gene ID 183
Other Names Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin 1-10, Angiotensin I, Ang I, Angiotensin-2, Angiotensin 1-8, Angiotensin II, Ang II, Angiotensin-3, Angiotensin 2-8, Angiotensin III, Ang III, Des-Asp[1]-angiotensin II, Angiotensin-4, Angiotensin 3-8, Angiotensin IV, Ang IV, Angiotensin 1-9, Angiotensin 1-7, Angiotensin 1-5, Angiotensin 1-4, AGT, SERPINA8
Target/Specificity This AGT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human AGT.
Dilution WB~~1:100~1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAGT Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGT
Synonyms SERPINA8
Function Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-3: stimulates aldosterone release.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)

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The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.


Desong, Liu., et al. J Renin Angiotensin Aldosterone Syst 11(4):248-255(2010)
Procopciuc, L.M., et al. Eur. J. Intern. Med. 21(5):414-418(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Hajjar, I., et al. J Am Geriatr Soc 58(6):1035-1042(2010)
Kiec-Wilk, B., et al. Prz. Lek. 67(3):151-156(2010)

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$ 295.00
$ 99.00
Cat# AM2173b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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