|Application ||WB, E|
|Calculated MW||38714 Da|
|Other Names||Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35, ANXA1, ANX1, LPC1|
|Target/Specificity||Purified His-tagged ANXA1 protein was used to produced this monoclonal antibody.|
|Format||Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ANXA1 Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.|
|Cellular Location||Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages.|
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Provided below are standard protocols that you may find useful for product applications.
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
Wallner B.P., et al. Nature 320:77-81(1986).
Kovacic R.T., et al. Biochemistry 30:9015-9021(1991).
Arcone R., et al. Eur. J. Biochem. 211:347-355(1993).
Varticovski L., et al. Biochemistry 27:3682-3690(1988).
Biemann K., et al. Science 237:992-998(1987).
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