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CTSD Antibody

Mouse Monoclonal Antibody (Mab)

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  • WB - CTSD Antibody AM2221b
    Anti-CTSD Antibody at 1:2000 dilution + U-251 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 44 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - CTSD Antibody AM2221b
    Immunohistochemical analysis of paraffin-embedded H. liver section using CTSD Antibody(Cat#AM2221B). AM2221B was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • WB - CTSD Antibody AM2221b
    CTSD Antibody(Cat. #AM2221b) western blot analysis in MCF-7,U251,HepG2 cell line lysates (35μg/lane).This demonstrates the CTSD antibody detected the CTSD protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07339
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 892CT11.1.1
Calculated MW 44552 Da
Additional Information
Gene ID 1509
Other Names Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD
Target/Specificity Purified His-tagged CTSD protein was used to produced this monoclonal antibody.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTSD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CPSD
Function Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Cellular Location Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).
Tissue Location Expressed in the aorta extrcellular space (at protein level).
Research Areas
Citations ( 0 )


Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.


Burkard T.R., et al. BMC Syst. Biol. 5:17-17(2011).
Faust P.L., et al. Proc. Natl. Acad. Sci. U.S.A. 82:4910-4914(1985).
Westley B.R., et al. Nucleic Acids Res. 15:3773-3786(1987).
Redecker B., et al. DNA Cell Biol. 10:423-431(1991).
Ebert L., et al. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 99.00
Cat# AM2221b
(40 western blots)
Availability: In Stock
Bulk Size
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