|Application ||WB, E|
|Calculated MW||12074 Da|
|Other Names||Tumor suppressor candidate 2, Fusion 1 protein, Fus-1 protein, PDGFA-associated protein 2, TUSC2, C3orf11, FUS1, LGCC, PDAP2|
|Target/Specificity||This TUSC2 antibody is generated from a mouse immunized with a recombinant protein of human TUSC2.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TUSC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C3orf11, FUS1, LGCC, PDAP2|
|Function||May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.|
|Tissue Location||Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta|
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Provided below are standard protocols that you may find useful for product applications.
May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
Kondo M.,et al.Oncogene 20:6258-6262(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Uno F.,et al.Cancer Res. 64:2969-2976(2004).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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