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TUSC2 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75896 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1,k |
| Clone/Animal Names | 1550CT388.74.12 |
| Calculated MW | 12074 Da |
| Gene ID | 11334 |
|---|---|
| Other Names | Tumor suppressor candidate 2, Fusion 1 protein, Fus-1 protein, PDGFA-associated protein 2, TUSC2, C3orf11, FUS1, LGCC, PDAP2 |
| Target/Specificity | This TUSC2 antibody is generated from a mouse immunized with a recombinant protein of human TUSC2. |
| Dilution | WB~~1:2000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TUSC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TUSC2 |
|---|---|
| Synonyms | C3orf11, FUS1, LGCC, PDAP2 |
| Function | May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. |
| Tissue Location | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
References
Kondo M.,et al.Oncogene 20:6258-6262(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Uno F.,et al.Cancer Res. 64:2969-2976(2004).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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