|Application ||WB, E|
|Other Accession||Q5E987, Q9Z2U1|
|Calculated MW||26411 Da|
|Other Names||Proteasome subunit alpha type-5, 22.214.171.124, Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain, PSMA5|
|Target/Specificity||This PSMA5 antibody is generated from a mouse immunized with a recombinant protein between 1-241 amino acids from human PSMA5.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PSMA5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||Expressed in fetal brain (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
DeMartino G.N.,et al.Biochim. Biophys. Acta 1079:29-38(1991).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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