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GABA Transporter (GAT) 1 Antibody

Affinity purified rabbit polyclonal antibody

  • WB - GABA Transporter (GAT) 1 Antibody AN1128
    Western blot of rat hippocampal homogenate showing specificimmunolabeling of the~ 67k GAT-1 protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23978
Reactivity Rat
Predicted Mouse
Host Rabbit
Clonality polyclonal
Calculated MW 67 KDa
Additional Information
Gene ID 79212
Gene Name SLC6A1
Other Names Sodium- and chloride-dependent GABA transporter 1, GAT-1, Solute carrier family 6 member 1, Slc6a1, Gabt1, Gat-1, Gat1
Target/Specificity Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Dilution WB~~ 1:1000
Format Prepared from rabbit serum by affinity purification.
Antibody Specificity Specific for the ~67k GAT-1 protein. Immunolabeling is blocked by the peptide used as antigen.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGABA Transporter (GAT) 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
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Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).


Minelli A, Brecha NC, Karschin C, DeBiasi S, Conti F (1995) GAT-1, a high-affinity GABA plasma membrana transporter, is localizad to neurons and astroglia int he cerebral cortex. J. Neurosci. 15(11):7734-7746.
Zhao WJ, Ma YH, Fei J, Mei ZT, Guo LH (2003) Increase in drug-induced seizure susceptibility of transgenic mice overexpressing GABA transporter 1. Acta Pharmacol. Sin. 24(10):991-5.

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$ 335.00
Cat# AN1128
(40 western blots)
Availability: 7-10 days
Bulk Size
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