|Application ||WB, E|
|Calculated MW||14719 Da|
|Description||FABP4: fatty acid binding protein 4, adipocyte. FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.|
|Immunogen||Purified recombinant fragment of FABP4 (aa61-121) expressed in E. Coli.|
|Formulation||Ascitic fluid containing 0.03% sodium azide. |
|Other Names||Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4, FABP4|
|Dilution||WB~~1/500 - 1/2000|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FABP4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity)|
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Provided below are standard protocols that you may find useful for product applications.
1. J Biol Chem. 2004 Dec 10;279(50):52399-405. 2. Mol Cell Proteomics. 2005 Apr;4(4):570-81.
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