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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   Myeloperoxidase Antibody   

Myeloperoxidase Antibody

Purified Mouse Monoclonal Antibody

  • WB - Myeloperoxidase Antibody AO1249a
    Figure 1: Western blot analysis using MPO mouse mAb against truncated Trx-MPO recombinant protein (1),truncated MBP-MPO (aa1-193) recombinant protein (2) and truncated MPO(aa165-745)-hIgGFc transfected CHO-K1 cell lysate(3).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05164
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 9B12G7; 4D8B12; 9B12D9; 9C11A5
Isotype IgG1
Calculated MW 83869 Da
Description Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.
Immunogen Purified recombinant fragment of MPO (aa1-193) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 4353
Other Names Myeloperoxidase, MPO,, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMyeloperoxidase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPO
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Cellular Location Lysosome.
Research Areas
Citations (0)

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1. J Pediatr Hematol Oncol. 2007 May;29(5):293-7. 2. PLoS ONE. 2008 Jun 30;3(7):e2816.

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$ 325.00
Cat# AO1249a
(40 western blots)
Availability: 7-10 days
Bulk Size
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