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CER1 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | O95813 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 9D6 |
| Isotype | IgG1 |
| Calculated MW | 30kDa |
| Description | CER1: cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis). Ii is a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. |
| Immunogen | Purified recombinant fragment of human CER1 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 9350 |
|---|---|
| Other Names | Cerberus, Cerberus-related protein, DAN domain family member 4, CER1, DAND4 |
| Dilution | WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 FC~~1:200~~400 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CER1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CER1 |
|---|---|
| Synonyms | DAND4 |
| Function | Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP- inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity). |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
1. Dev Biol. 1998 Feb 15;194(2):135-51. 2. Growth Factors. 2004 Dec;22(4):233-41. 3. PLoS One. 2009;4(4):e5302.
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