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CDC25C AntibodyMouse Monoclonal Antibody to CDC25C
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AO1357a | 0.1ml 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
CDC25C Antibody - Product info | |
| Application | WB
|
| Primary Accession | P30307 |
| Other Accession | NP_073720.1 |
| Reactivity | Human |
| Isotype | Mouse IgG1 |
| Clone Names | 1F12 |
| Calculated MW | 53365 Da |
CDC25C Antibody - Additional info | |
| Gene ID 995 | |
| Other Names CDC25; CDC25C | |
| Target/Specificity Purified recombinant fragment of human CDC25C expressed in E. Coli. | |
| Dilution WB~~1:500 - 2000. | |
| Format Purified recombinant fragment of human CDC25C expressed in E. Coli. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions CDC25C Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
CDC25C Antibody - Protein Information | |
| Name CDC25C | |
| Function Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity | |
| Cellular Location Nucleus. | |
CDC25C Antibody - Related products
AM1908a: CDC25C Antibody (ascites)
AP7862b: CDC25C Antibody (C-term)
AP7862d: CDC25C Antibody (Center)
RI10921: CDC25C predesign siRNA
LY11518a: CDC25C Over-expression Lysate
BP7862b: CDC25C Antibody (C-term) Blocking Peptide
BP7862d: CDC25C Antibody (Center) Blocking Peptide
AT1458a: CDC25C Antibody (monoclonal) (M01)
CDC25C Antibody - Application data
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Figure 1: Western blot analysis using anti-CDC25C mAb against Hela(1), K562(2), PC-3(3), HEK293(4) and Raw264.7(5) cell lysate.
CDC25C Antibody - Research Areas
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BACKGROUND
Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
REFERENCES
1. Cancer Cell. 2007 Mar;11(3):275-89.
2. Int J Biochem Cell Biol. 2007;39(9):1707-13.
3. Int J Cancer. 2010 May 1;126(9):2199-210.
