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MUM1 Antibody

Purified Mouse Monoclonal Antibody

  • WB - MUM1 Antibody AO1401a
    Figure 1: Western blot analysis using MUM1 mAb against human MUM1 (AA: 590-711) recombinant protein. (Expected MW is 39.8 kDa)
  • IHC - MUM1 Antibody AO1401a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human melanoma (A), non-Hodgkin`s lymphoma (B), using MUM1 mouse mAb with DAB staining.
  • IHC - MUM1 Antibody AO1401a
    Figure 3: Immunohistochemical analysis of paraffin-embedded human Uterus tissues using MUM1 mouse mAb
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q2TAK8
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4G10
Isotype IgG1
Calculated MW 78.6kDa
Description Mutated melanoma-associated antigen 1 (MUM1) is a 78 kDa protein encoded by the MUM1 gene. MUM1 is expressed in a subset of B cells in the light zone of the germinal center, plasma cells, activated T cells and a wide spectrum of related hematolymphoid neoplasms. Antibodies to MUM1 are useful in the sub classification of lymphoid malignancies.
Immunogen Purified recombinant fragment of human MUM1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 84939
Other Names PWWP domain-containing protein MUM1, Mutated melanoma-associated antigen 1, MUM-1, Protein expandere, MUM1, EXPAND1
Dilution WB~~1/500 - 1/2000
IHC~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMUM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MUM1
Synonyms EXPAND1
Function Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Cellular Location Nucleus. Note=Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1
Research Areas
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1. Genome Res. 1996 Sep;6(9):791-806. 2. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903.

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$ 325.00
Cat# AO1401a
(40 western blots)
Availability: 7-10 days
Bulk Size
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