|Application ||WB, IHC, ICC, E|
|Description||Kelch-like protein 11, Subcellular location Secreted.|
|Immunogen||Purified recombinant fragment of human KLHL11 expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||Kelch-like protein 11, KLHL11|
|Dilution||WB~~1/500 - 1/2000|
IF~~1/200 - 1/1000
IHC~~1/500 - 1/2000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLHL11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.|
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1. Gerhard DS, et al. Genome Res, 2004 Oct. 2. Ota T, et al. Nat Genet, 2004 Jan. 3. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24.
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