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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   KLHL1 Antibody   

KLHL1 Antibody

Purified Mouse Monoclonal Antibody

  • WB - KLHL1 Antibody AO1462a
    Figure 1: Western blot analysis using KLHL1 mAb against human KLHL1 (AA: 202-506) recombinant protein. (Expected MW is 60.2 kDa)
  • IF - KLHL1 Antibody AO1462a
    Figure 2: Immunofluorescence analysis of NIH/3T3 cells using KLHL1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NR64
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3A8
Isotype IgG1
Calculated MW 82kDa
Description The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.
Immunogen Purified recombinant fragment of human KLHL1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 57626
Other Names Kelch-like protein 1, KLHL1, KIAA1490
Dilution WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKLHL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL1
Synonyms KIAA1490
Function May play a role in organizing the actin cytoskeleton of the brain cells.
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Highly expressed in brain.
Research Areas
Citations (0)

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1. DNA Res. 2000 Apr 28;7(2):143-50. 2. Nat Genet. 2004 Jan;36(1):40-5. 3. Science. 2005 Mar 11;307(5715):1621-5.

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$ 325.00
Cat# AO1462a
(40 western blots)
Availability: 7-10 days
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